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ARE MEDICATIONS AND SUPPLEMENTS EFFECTIVE IN WEIGHT LOSS?

Obesity is associated with significant morbidity and affects how individuals function in their daily life. It includes social interactions, work performance, and sleep patterns. The degree of obesity seems to influence the quality of life in several domains. However, using a weight loss pill, doing regular exercises, and eating a supportive diet can assist in shedding unnecessary weight. The presence of comorbidities related to overweight adds even more burden to these patients. All this has significant economic implications because medical costs associated with obesity are estimated to be twice as high as those associated with smoking.

What can lead to being obese?

The main factor that encourages the development of overweight is an energy intake greater than energy expenditure. Many factors influence this balance, including genetics, diet, environment, behavior patterns, socio-economic situation, and physical activity degree.

Why should a person maintain a healthy weight?

Weight loss is associated with improvement or complete resolution of several comorbidities, which are more prevalent in the obese population. It may include diabetes mellitus, hypertension, dyslipidemia, sleep apnea syndrome, and osteoarthritis. However, weight loss should be considered an adjunct to these therapies rather than a substitute because it does not replace pharmacologic and surgical treatments.

People can shed additional weight by behavior modifications that include diet, physical activity, using a weight loss pill, and behavioral therapy. In addition to these interventions, pharmacological agents are an aid to lifestyle changes in reducing weight and improving comorbidities.

What are the benefits of a healthy weight?

If you are overweight, your risk of disease increases significantly. You may be more likely to suffer from heart disease, type 2 diabetes, and osteoarthritis. If you are an overweight smoker, the adverse effects on your health can be even greater. In addition to increasing your risk of many diseases, being obese or very overweight makes treatment difficult for many existing health problems.

  • Improvement in your health

Having more body fat than normal means that you are exposed to increased amounts of estrogen. This hormonal imbalance may increase the risk of breast cancer in women and prostate cancer in men. Conversely, losing excess weight reduces these risks. Additional body fat around the waist damages the liver and kidneys. It can reduce your body’s ability to function properly.

  • Reduces the risk of diseases

Weight loss benefits type 2 diabetes According to a study published in November 2011 in “Diabetes Care,” women who lost 9% of their body weight reduced their risk of developing type 2 diabetes by 50%. Men with a similar weight loss showed a 35% reduction in risk. Using a weight loss pill can also help burn unnecessary weight. However, you should always consult with your doctor before using any medicine.

Other diseases caused by obesity are-

  • Heart disease
    • Increased cholesterol
    • High blood pressure
    • Stroke, coronary artery disease (CAD) and other cardiovascular diseases
  • Diminishes the threat of osteoarthritis

A healthy body mass can trim down the risk of osteoarthritis. It is a degenerative condition that causes pain and swelling in the joints. Some studies have found a link between obesity and osteoarthritis, suggesting that weight loss may help reduce symptoms of this disease.

  • Lessens the possibility of gall bladder disease

Gallbladder disease is caused by the formation of stones in the gallbladder. Losing weight decreases your risk of this disease. However, you can get rid of obesity in various ways. They may include using a weight loss pill, regular exercises, taking a supportive diet, and other therapies.

  • Improves fertility

Weight loss benefits infertility. Excess body fat may reduce your chance of becoming pregnant during fertility treatments such as in-vitro fertilization (IVF). A study published in September 2011 in “Obstetrics and Gynecology” found that women with a body mass index over 29 were less likely to have a live birth after IVF treatment compared to women who had a normal BMI.

  • Enhances sleeping patterns

People with a healthy body weight see an improvement in sleep apnea. Women who lost weight through healthy eating and exercise reduced their risk of developing obstructive sleep apnea by 63%, according to a study published in August 2011 in “Lung India.”

Sleep apnea occurs when the airway becomes blocked during sleep, disrupting breathing and can lead to snoring.

  • Reduces danger of colon cancer

Shedding an unnecessary body mass can diminish the risk of colon cancer. People who are overweight or obese have an increased risk of colon cancer compared with people who maintain a healthy weight. A study published in January 2012 in “Cancer Epidemiology, Biomarkers and Prevention” reported that participants who lost 5 -10% of their body weight reduced their risk of developing colorectal cancer by 14%.

  • Improves stress levels

Weight loss benefits stress levels. Losing weight has a positive effect on your emotional health. Stress is very harmful to your physical and mental well-being. Therefore, shedding unnecessary body mass is a favor you can do to yourself. You can use a weight loss pill, do regular exercises and take healthy foods to support your journey.

  • Helps treat PCOS

Burning undue fat improves fertility in women with polycystic ovary syndrome (PCOS). Many pieces of research show that obese women with PCOS who lost at least 5% of their body weight had a greater chance of becoming pregnant when compared to obese women with PCOS who did not lose weight.

  • Improves blood sugar

Blood sugar levels are likely to improve when people lose weight. A study published in September 2011 in “Diabetes Care” found that people with type 2 diabetes who lost at least 6% of their body weight reduced their blood sugar levels to normal ranges.

Studies have found that overweight and obese people who lost weight through eating healthy foods, exercising regularly, and getting more sleep experienced health benefits.

What medications can help lose weight?

Doctors prescribe medications to lose weight in certain circumstances. If a person is unable to shed extra body fat with diet and exercise, they may recommend people using these pills.

Xenical

Xenical (Orlistat) is the prescription-only weight loss pill, which works by preventing some of the fat in your food from being absorbed into your body. The medication was developed as a prescription drug for the treatment of obesity. Orlistat is one of many prescribed weight-loss medications, and it is not exactly clear how it works. However, most professionals agree that this medicine prevents some fat from being absorbed by your body.

Xenical is used with a reduced-calorie diet and with increased physical activity in the treatment of obesity.

How effective is Xenical?

Orlistat can help you lose weight if combined with a reduced-calorie diet and exercise, but it’s unlikely to lead to significant weight loss on its own. Xenical works best when combined with a healthy balanced diet and exercise.

Does it work for everyone?

Xenical doesn’t work for everyone. Nevertheless, if taken as directed, it can lead to a weight loss of about 5-10% over 12 weeks. Doctors prescribe using the medication in combination with healthy eating and exercise to achieve more significant weight loss results. A full course of Xenical treatment typically lasts 12 weeks, but you shouldn’t take this weight loss pill for more than 12 months.

What are the side effects of Xenical?

The most common side effect is flatulence with discharge. It usually happens when you start taking Xenical and is due to the undigested fat in your bowel. Moreover, other common side effects include-

  • Loose or more frequent stools
  • Oily spotting
  • An urgent need to go to the toilet
  • An unpleasant taste in the mouth and stomach pain

Although in rare cases, some people experience indigestion, abdominal pain, headache, nausea, or vomiting.

What are the other weight loss drugs like Orlistat?

There are many different weight loss drugs currently on the market. Xenical is only one of many prescription medications that can help you shed extra body fat. It was originally developed as a treatment for obesity. However, it can also assist in managing type-2 diabetes and lowering blood pressure.

The main class of weight-loss medications is known as lipase inhibitors. Orlistat belongs to a subgroup known as the pancreatic enzyme inhibitor, which stops some of the fat in your food from being absorbed into your body. Moreover, other medications in this class include-

  • Acarbose (Precose)
  • Miglitol (Glyset)
  • Pramlintide (Symlin)

Can supplements work better than a weight loss pill?

Many people want to get rid of obesity by burning more calories than they eat. It can be done in different ways, for example by exercising daily or eating healthy. However, some supplements also claim to help burn some extra calories while you are just sitting still. Some of these supplements are-

  • L-Carnitine

L-Carnitine burns more calories during workouts and stress. It is an amino acid that plays a role in metabolism, helping the body turn fat into energy. Moreover, this supplement also has anti-aging properties because it can protect mitochondria, structures inside cells that produce energy.

  • Chromium

Chromium increases glucose tolerance, which can lead to weight loss. It is a trace mineral that helps with sugar cravings and food intake. This supplement works by increasing the ability of cells to use insulin, a hormone that helps glucose enter our cells from the blood. A study published in The Journal of Nutrition found that Chromium increases LDL (bad) cholesterol. However, it does not seem to affect blood pressure, body weight, or body composition. Chromium can help control your appetite because it reduces cravings for carbohydrates and high-fat foods. However, if you use a weight loss pill, consult your doctor if using medications in combination with supplements benefits your health.

  • Garcinia cambogia

Garcinia cambogia suppresses appetite. Overcoming your hunger is one of the best ways to lose weight because it helps you cut down on calories. A study found that taking just two servings of Garcinia Cambogia per day could help reduce meal size by up to 40%. It works because hydroxycitric acid (HCA), an active ingredient in this supplement, can reduce your craving and lower the number of calories you eat.

  • Green tea extract

Extract of green tea boosts fat burning. Green tea can improve metabolism and reduce the risk of cardiovascular diseases, Alzheimer’s, and Parkinson’s disease. Moreover, it’s also beneficial for weight loss. A study found that it could help enhance fat burning by three to four times during moderate exercise, especially when combined with caffeine. Green tea also contains antioxidants called catechins, which have been linked with increased metabolism and lower body weight in some studies.

  • CoQ10

This supplement increases exercise capacity and decrease fatigue. CoQ10 is a compound your body produces on its own. However, it can also be found in foods such as beef or sardines. It has been studied for years because of the significant role it plays in energy production. A study published in The Journal of Sports Medicine and Physical Fitness found that muscle CoQ10 concentrations were significantly lower in obese individuals than lean people. Moreover, obese people who used CoQ10 for around eight weeks decreased total body mass and increased fat oxidation.

Consult with your healthcare provider if you can use a weight loss pill along with the supplement.

  • Raspberry ketones

Raspberry ketones raise the level of adiponectin. It is a protein hormone produced by fat cells, which has a crucial role in metabolism and energy expenditure. A study found that obese patients who took raspberry ketone supplements for 12 weeks increased their adiponectin concentrations by an impressive percentage of 31 on average. What’s more, the ratio of adiponectin to leptin also improved, which means that this supplement can help improve your metabolism.

  • Caffeine

Caffeine boosts the basal metabolic rate. This well-known stimulant is found in coffee, tea, chocolate, certain soft drinks, and energy drinks. Numerous studies have shown that caffeine has many health benefits on the nervous system, heart, liver, and kidneys. Moreover, it also increases the metabolism by stimulating the production of adrenaline, which causes an increase in blood pressure and fat oxidation.

Caffeine has many proven benefits for health. It is more effective when combined with other ingredients. However, caffeine can also cause side effects such as insomnia, nausea, and anxiety. You should also avoid taking caffeine before bed because you need to sleep properly to feel rested and full of energy the following day.

These are medications and supplements, which can lend you a hand in shedding unnecessary body mass. However, it is wise to seek the opinion of your healthcare provider before using any weight loss pill or supplement. It will help prevent complications.